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4 hne  (Bioss)


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    Bioss 4 hne
    4 Hne, supplied by Bioss, used in various techniques. Bioz Stars score: 96/100, based on 229 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/4 hne/product/Bioss
    Average 96 stars, based on 229 article reviews
    4 hne - by Bioz Stars, 2026-03
    96/100 stars

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    Enhanced ferroptosis in patients with POAG and the COH rat model. ( A – D ) The levels of ferroptosis-related markers (iron ion, MDA, GPX4, and GSH) in human aqueous humor, n = 10. ( E ) Elevated IOP in COH rats was induced significantly at 4 weeks, n = 6. ( F , G ) The levels of MDA and GPX4 in the aqueous humor of COH rats, n = 6. ( H ) H&E <t>staining,</t> <t>4-HNE</t> IHC staining, and IF staining of COH models. In IF images, red indicates the 4-HNE staining and blue indicates DAPI (nuclei). * P < 0.05, ** P < 0.01, *** P < 0.001. S cale bar : 100 µm (20×), 50 µm (40×). The arrow refers to TM. OS, left eyes; OD, right eyes; SC, Schlemm's canal; TM, trabecular meshwork.
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    Enhanced ferroptosis in patients with POAG and the COH rat model. ( A – D ) The levels of ferroptosis-related markers (iron ion, MDA, GPX4, and GSH) in human aqueous humor, n = 10. ( E ) Elevated IOP in COH rats was induced significantly at 4 weeks, n = 6. ( F , G ) The levels of MDA and GPX4 in the aqueous humor of COH rats, n = 6. ( H ) H&E staining, 4-HNE IHC staining, and IF staining of COH models. In IF images, red indicates the 4-HNE staining and blue indicates DAPI (nuclei). * P < 0.05, ** P < 0.01, *** P < 0.001. S cale bar : 100 µm (20×), 50 µm (40×). The arrow refers to TM. OS, left eyes; OD, right eyes; SC, Schlemm's canal; TM, trabecular meshwork.

    Journal: Investigative Ophthalmology & Visual Science

    Article Title: Digoxin Attenuates Ocular Hypertension and Protects Trabecular Meshwork Cells via Ferroptosis Inhibition

    doi: 10.1167/iovs.67.1.46

    Figure Lengend Snippet: Enhanced ferroptosis in patients with POAG and the COH rat model. ( A – D ) The levels of ferroptosis-related markers (iron ion, MDA, GPX4, and GSH) in human aqueous humor, n = 10. ( E ) Elevated IOP in COH rats was induced significantly at 4 weeks, n = 6. ( F , G ) The levels of MDA and GPX4 in the aqueous humor of COH rats, n = 6. ( H ) H&E staining, 4-HNE IHC staining, and IF staining of COH models. In IF images, red indicates the 4-HNE staining and blue indicates DAPI (nuclei). * P < 0.05, ** P < 0.01, *** P < 0.001. S cale bar : 100 µm (20×), 50 µm (40×). The arrow refers to TM. OS, left eyes; OD, right eyes; SC, Schlemm's canal; TM, trabecular meshwork.

    Article Snippet: For immunohistochemistry (IHC), after antigen retrieval, the sections were incubated overnight with 4-HNE antibody (BIOSS, Beijing, China, bs-6313R) at 4°C.

    Techniques: Staining, Immunohistochemistry

    The effects of digoxin on ferroptosis in vivo. H&E, 4-HNE, SLC2A3, HBA1, SCD, α-SMA, and COL-1 staining in the representative COH models. In IF staining, red represents the target protein (4-HNE, SLC2A3, HBA1, SCD, α-SMA, and COL-1), and blue indicates DAPI (nuclei). Scale bar : 50 µm (40×). The arrow refers to corresponding indicators. SC, Schlemm's canal; TM, trabecular meshwork.

    Journal: Investigative Ophthalmology & Visual Science

    Article Title: Digoxin Attenuates Ocular Hypertension and Protects Trabecular Meshwork Cells via Ferroptosis Inhibition

    doi: 10.1167/iovs.67.1.46

    Figure Lengend Snippet: The effects of digoxin on ferroptosis in vivo. H&E, 4-HNE, SLC2A3, HBA1, SCD, α-SMA, and COL-1 staining in the representative COH models. In IF staining, red represents the target protein (4-HNE, SLC2A3, HBA1, SCD, α-SMA, and COL-1), and blue indicates DAPI (nuclei). Scale bar : 50 µm (40×). The arrow refers to corresponding indicators. SC, Schlemm's canal; TM, trabecular meshwork.

    Article Snippet: For immunohistochemistry (IHC), after antigen retrieval, the sections were incubated overnight with 4-HNE antibody (BIOSS, Beijing, China, bs-6313R) at 4°C.

    Techniques: In Vivo, Staining